Context: https://en.wikipedia.org/wiki/President%27s_Malaria_Initiative
The President's Malaria Initiative (PMI) is a U.S. Government initiative to control and eliminate malaria, one of the leading global causes of premature death and disability.\1]) The initiative was originally launched by U.S. president George W. Bush in 2005, and has been continued by each successive U.S. president.\2])
PMI was originally created with a mission to "reduce malaria-related mortality by 50 percent across 15 high-burden countries in sub-Saharan Africa".\2]) PMI has since expanded to 24 malaria-endemic countries in sub-Saharan Africa and 3 additional countries in the Greater Mekong Subregion of Southeast Asia, where it seeks to further reduce malaria burden and assist countries in achieving malaria elimination.\3])
PMI works closely with national malaria programs and global partners including the World Health Organization, Roll Back Malaria, and Global Fund.\4]) Global malaria efforts, including those of PMI, have cut malaria mortality by over 60%, saved 7.6 million lives, and prevented 1.5 billion malaria cases globally between 2000 and 2019.\5]) PMI has supported malaria prevention and control for over 500 million at-risk people in Africa.\3])
https://en.wikipedia.org/wiki/President%27s_Emergency_Plan_for_AIDS_Relief
The United States President's Emergency Plan For AIDS Relief (PEPFAR) is the global health funding by the United States to address the global HIV/AIDS epidemic and help save the lives of those suffering from the disease. According to the United States government, as of 2023, PEPFAR has saved over 25 million lives,\1])\2]) primarily in sub-Saharan Africa.\3])\4])
Launched by U.S. President George W. Bush in 2003, as of August 2024, PEPFAR has provided cumulative funding of $120 billion for HIV/AIDS treatment, prevention, and research since its inception, making it the largest commitment by any nation focused on a single disease in history.\3]) PEPFAR is implemented by a combination of U.S. government agencies in over 50 countries and overseen by the Global AIDS Coordinator at the United States Department of State.\5])
PEPFAR supports HIV prevention, testing and antiretroviral treatment, as well as prevention of mother-to-child transmission, care for orphans and vulnerable children, tuberculosis services for people with HIV and broader health-system strengthening. The program initially focused on emergency treatment and prevention, later shifting toward partnership frameworks with recipient governments, epidemic control targets and long-term sustainability. By September 2025, PEPFAR was credited with saving more than 26 million lives and preventing 7.8 million infants from acquiring HIV at birth.\6])
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